Growth Factors
In order to grow humans require two specific hormones that are found in the body. At times some people are deficient in these hormones, either for biological reasons or cultural reasons. Malnutrition can lead to the lack of hormones required for growth in the body. These two hormones are called HGH, the human growth hormone, and the IGF-1, the Insulin Growth Factor.
IGF-1 is also known as Somatomedin C and is a product of HGH. The pituitary gland in the brain will signal the excretion of HGH into the body. HGH then signals the liver to create IGF-1, promoting growth. When children lack the ability to grow they are normally prescribed HGH for natural production. When adults, normally those with certain forms of dwarfism, lack these hormones they are often prescribed IGF-1.
Once released HGH is difficult to test as it is rapidly absorbed into the liver. IGF-1 is easier to measure, thus why adults with hormonal imbalances are prescribed IGF-1 over HGH. The levels of IGF-1 will steadily increase from ages nine to about age sixteen before they level out completely. Males and females have different amounts during this time.
The natural benefits of HGH are the result of growth factors in the body, such as both IGF-1 and IGF-2. IGF-1 can allow different parts of the body to produce cells, including the skin, the liver, the kidneys, and muscles. This hormones helsp produce cells of all different systems to coordinate growth, regeneration, death, and function at the same time. These include the nervous system, the hormonal system, and the immune system.
IGF-1 is also required in transferring glucose from cell membranes and supplying raw materials to cells for repair and growth necessities. After a certain time, HGH production in the brain will slow, leading to the slowing of IGF-1 in the liver. This slowing happens as people leave their teenage years and finish puberty. This is called the resting phase. While in resting phase IGF-1 will also help complete DNA synthesis. This hormone is also associated with degeneration of the body in elderly people.